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Welcome to Prasanna Laboratory!

Dr. Prasanna's laboratory is part of the Department of Biomedical Engineering, a joint department within the School of Medicine and School of Engineering. Overall research theme in Prasanna's laboratory is to understand the mechanisms of cardiovascular diseases and develop innovative new therapies using technologies in modern medicine and bioengineering. Dr. Krishnamurthy’s laboratory focuses on several broad research areas: I) to study the molecular mechanisms involved in the progression of cardiovascular diseases II) understand how diabetes influences cardiovascular pathophysiology III) develop novel therapeutic strategies- to enhance stem cell therapeutic benefits (involving adult cells and induced pluripotent stem cells) and to promote cardiac regeneration and repair. Our laboratory uses molecular biology and modern classical research tools along with relevant surgical mouse models of cardiac diseases including myocardial infarction (LAD ligation), ischemia reperfusion and hypertrophy (ANG-II and TAC induced). Long-term goal of these studies is to identify new targets that can aid in development of future drugs and new therapies for prevention and treatment of cardiovascular disease complications in diabetes.

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About Dr. Krishnamurthy

Prasanna Krishnamurthy, MVSc, PhD, FAHA
Associate Professor
Department of Biomedical Engineering
School of Medicine and Engineering

Dr. Prasanna earned his BVSc (DVM) degree with honors from Bangalore Veterinary College and completed his Masters and PhD in Veterinary Pathology from Indian Veterinary Research Institute (India's premier institute for Veterinary Research). He completed his postdoctoral training at Northwestern University (in Dr. Raj Kishore's laboratory) and East Tennessee State University. Before joining UAB, he held faculty appointments at the Feinberg Cardiovascular Research Institute, Northwestern University School of Medicine, Chicago, Illinois and Houston Methodist Research Institute, Texas. 

As a member of the Department of Biomedical Engineering, he directs a research program focusing on understanding mechanisms of cardiovascular diseases and developing novel therapeutic strategies to promote cardiac regeneration and repair. Dr. Krishnamurthy’s laboratory is supported through funds from National Institutes of Health (NIH-R01) and American Heart Association (GIA and Postdoctoral fellowships). Prasanna's current interests include innovation of novel therapeutic strategies to repair cardiovascular damage through research, propel research through collaborations, bringing additional research funding and spending quality time with family and friends.