Description:  Major advances have been made in understanding diseases of the nervous system at the cellular and molecular levels. Several new findings have had direct therapeutic implications and have resulted in the development of novel drugs or new disease management strategies. This course intends to review the most studied nervous system disorders.

Objectives:  The course seeks to familiarize students with the current state-of-the-field with regard to knowledge of the most well studied disorders of the nervous system.  Students will have the opportunity to develop and execute formal lectures and lead journal club discussions.

Limitations and Course Requirements: The course is designed for graduate and medical student. The course is limited to 24 participants; for-credit participation is required. Post-Doctoral trainees, Interns or Residents are invited to participate only if registered for credit.

Course Format: The course is a problem-based small group session that will be largely taught by students. Faculty with active research programs on specific nervous system diseases will be available to coach students and help them prepare lectures. Each 2-hour meeting will cover one disease. Students will develop a lecture for the class to introduce the advances made in the cellular and molecular biology of the disease. This lecture should also provide the necessary background to understand the paper.  Student presenters will then transition to leading the class through a recent basic science paper relevant to the disease being discussed. All students are expected to actively participate during each daily discussion.