Dr. Meador-Woodruff received his BS in Chemistry from the University of Richmond, and his MD from the Medical College of Virginia. He then moved to Ann Arbor, and completed a combined residency in psychiatry and a research fellowship at the University of Michigan. After completing his research training, he joined the faculty of the Department of Psychiatry and the Mental Health Research Institute at the University of Michigan, where he held administrative positions including Associate Chair for Research and Vice Chair. He left Michigan in April 2006 to become the Heman E. Drummond Professor and Chairman of the Department of Psychiatry of University of Alabama at Birmingham (UAB). He moved his lab largely intact to UAB.
His research has been continuously funded by NIH since 1989. His laboratory's primary research interest is on understanding how different parts of the brain communicate with other parts via a variety of chemical signals, and how this communication is disrupted in schizophrenia. His current focus is on studying the expression of genes associated with glutamatergic neurotransmission within individual cells in the nervous system.
He has a longstanding interest in teaching and mentorship, and nearly 100 trainees have rotated through his lab. He was director of the University of Michigan's Psychiatry Residency Research Track, and was the PI of one of the earliest NIMH R25 grants to fund such research exposure during residency training. He is the Editor-in-Chief of the journal Neuropsychopharmacology.